After I have determined my story, the sequence of events, and the layout of ALL the pages, I draw out all the pages on regular cover stock with a mechanical pencil. Above is an example of a page. I draw close to the size I print at, and the above page measures 8.5x5.5".
Then when I have pencilled every page I photocopy them around 150-160% of the original size. As you can see the results are nice and dark.
Then I tape some very good paper (Strathmore Bristol board) on top of the photo copied page and turn on the light box! Thus illuminated i can see my original line work and then ink away.
After my hand does that spazy-clenchy-numbness thing I decide
Then I scan it, futz with it, correct it, develop acrimonious feeling towards it, and then BAM!; It's ready for print.